SYNTHESIS, CHARACTERISATION AND ANTIBACTERIAL ACTIVITY OF 2 - (PHENYL SULFONYL) AMINO PYRIDINE.

Authors

  • A.O. IJEOMAH
  • M.C. TSEEKA

DOI:

https://doi.org/10.46602/jcsn.v46i1.573

Abstract

The synthesis of 2-(phenylsulfonyl)amino pyridine is reported. This was achieved by sulfonylation of 2-aminopyridine using benzenesulfonyl chloride in alkaline medium while employing water as solvent. The structure of the synthesized compound was elucidated using the Ultra Violet, Fourier-transform infrared spectroscopy(FTIR) and Nuclear magnetic resonance (NMR) spectra data obtained. The antibacterial activity of the synthesized compound was tested on Staphylococcus aureus, Escherichia coli and Salmonella typhi using agar well diffusion method to establish the inhibition zone diameter for these microbes. The result of inhibition zone diameter obtained showed that the synthesized compound inhibited the growth of the test organisms and so have potential as an antimicrobial agent

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Published

2021-02-02

How to Cite

IJEOMAH, A., & TSEEKA, M. . (2021). SYNTHESIS, CHARACTERISATION AND ANTIBACTERIAL ACTIVITY OF 2 - (PHENYL SULFONYL) AMINO PYRIDINE . Journal of Chemical Society of Nigeria, 46(1). https://doi.org/10.46602/jcsn.v46i1.573

Issue

Vol. 46 No. 1 (2021): J. Chem. Soc. Nigeria

Section

Articles

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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.